{"gene":"PF3D7_1367500","run_date":"2026-09-08T14:19:06","timeline":{"discoveries":[],"current_model":"No mechanistic findings in the available literature specifically about PF3D7_1367500 (b5, NADH-cytochrome b5 reductase, putative) in Plasmodium falciparum; the retrieved papers either describe NADH-cytochrome b5 reductase activity in host tissues or other organisms rather than characterizing this specific Plasmodium protein mechanistically."},"narrative":{"mechanistic_narrative":"No mechanistic discoveries found in literature.","teleology":[],"mechanism_profile":null},"prefetch_data":{},"corpus_meta":[{"pmid":"145326","id":"PMC_145326","title":"Electron microscope cytochemistry of host-parasite membrane interactions in malaria.","date":"1977","source":"Bulletin of the World Health Organization","url":"https://pubmed.ncbi.nlm.nih.gov/145326","citation_count":35,"is_preprint":false,"source_species":["Pf"],"role":"primary","match_terms":["NADH"],"competing_organism_flag":false,"competing_organism_match":"","competing_organism_only":false},{"pmid":"3627173","id":"PMC_3627173","title":"Effect of Plasmodium yoelii nigeriensis infection and chloroquine on the hepatic mixed function oxidase system of mice.","date":"1987","source":"Molecular and biochemical parasitology","url":"https://pubmed.ncbi.nlm.nih.gov/3627173","citation_count":22,"is_preprint":false,"source_species":["Pf"],"role":"primary","match_terms":["NADH-cytochrome b5 reductase","NADH"],"competing_organism_flag":false,"competing_organism_match":"","competing_organism_only":false},{"pmid":"6083994","id":"PMC_6083994","title":"Histochemical observations on the exoerythrocytic malaria parasite Plasmodium berghei in rat liver.","date":"1984","source":"Histochemistry","url":"https://pubmed.ncbi.nlm.nih.gov/6083994","citation_count":15,"is_preprint":false,"source_species":["Pf"],"role":"primary","match_terms":["NADH"],"competing_organism_flag":false,"competing_organism_match":"","competing_organism_only":false},{"pmid":"4393193","id":"PMC_4393193","title":"Ultrastructural localisation of NADH- and NADPH-dehydrogenases in the erythrocytic stages of the rodent malaria parasite, Plasmodium berghei.","date":"1970","source":"Life sciences. Pt. 2: Biochemistry, general and molecular biology","url":"https://pubmed.ncbi.nlm.nih.gov/4393193","citation_count":13,"is_preprint":false,"source_species":["Pf"],"role":"primary","match_terms":["NADH"],"competing_organism_flag":false,"competing_organism_match":"","competing_organism_only":false},{"pmid":"42352277","id":"PMC_42352277","title":"Free Radical Formation in the Reactions of Redox-Active Drugs and Xenobiotics with Mitochondrial Flavoenzymes.","date":"2026","source":"Biomolecules","url":"https://pubmed.ncbi.nlm.nih.gov/42352277","citation_count":0,"is_preprint":false,"source_species":["Pf"],"role":"primary","match_terms":["NADH"],"competing_organism_flag":false,"competing_organism_match":"","competing_organism_only":false}],"cost":{"stage1":{"model":"claude-sonnet-4-6","input_tokens":4634,"output_tokens":115,"usd":0.007813,"stage1_stop_reason":"end_turn"},"stage2":{"model":"","input_tokens":0,"output_tokens":0,"usd":0.0},"total_usd":0.007813,"stage1_batch_id":"msgbatch_011BPjN2BL33F8cJXD1r7V7T","stage2_batch_id":"msgbatch_01Qwg6vP7qxkpL6Gsc7tajsb","note":"batch pricing = 50% of standard"},"stage1_raw":"```json\n{\n  \"discoveries\": [],\n  \"current_model\": \"No mechanistic findings in the available literature specifically about PF3D7_1367500 (b5, NADH-cytochrome b5 reductase, putative) in Plasmodium falciparum; the retrieved papers either describe NADH-cytochrome b5 reductase activity in host tissues or other organisms rather than characterizing this specific Plasmodium protein mechanistically.\"\n}\n```","stage2_raw":"","audit_flag":{"gene":"PF3D7_1367500","tier":"COVERAGE","verdict":"Coverage note","subtype":"corpus_unverifiable","uniprot_band":"empty","rules_fired":"R1","issue":"R1: record has no curated symbol, so its corpus cannot name it (named in 0/98); grounding untestable — coverage note, not a collision"},"strains":[{"strain":"Pf3D7","gene_id":"PF3D7_1367500","name":null,"product":"NADH-cytochrome b5 reductase, putative","uniprot_acc":null,"chromosome":null,"start_pos":null},{"strain":"PbANKA","gene_id":"PBANKA_1143400","name":null,"product":"NADH-cytochrome b5 reductase, putative","uniprot_acc":null,"chromosome":null,"start_pos":null},{"strain":"PkH","gene_id":"PKNH_1103700","name":null,"product":"NADH-cytochrome b5 reductase, putative","uniprot_acc":null,"chromosome":null,"start_pos":null}],"gene_symbol":"","evaluation":null}