{"gene":"PF3D7_1347500","run_date":"2026-09-08T14:19:06","timeline":{"discoveries":[{"year":2011,"finding":"ALBA4 (one of four PfAlba paralogs) was isolated as part of a molecular complex associated with the P. falciparum-specific TARE6 subtelomeric region, and shown by electromobility shift assays (EMSAs) to bind TARE6 repeat DNA sequences.","method":"Co-purification/complex isolation, EMSA","journal":"Nucleic acids research","confidence":"Medium","confidence_rationale":"Tier 2 / Weak — EMSA directly demonstrates DNA binding, but ALBA4 is one of three paralogs co-isolated and the abstract does not individually distinguish ALBA4's binding from the others; single lab, single study.","pmids":["22167473"],"is_preprint":false,"attribution":[{"species":"Plasmodium falciparum","strain":""}]},{"year":2011,"finding":"ALBA4 (as part of the PfAlba complex) binds single-stranded RNA (ssRNA) as demonstrated by EMSA, with different binding preferences among the paralogs; intracellular localization shifts from nuclear periphery in early blood stages to a cytoplasmic punctate pattern at trophozoite-schizont transition, indicating developmentally regulated subcellular localization.","method":"EMSA (ssRNA probes), fluorescence microscopy/immunolocalization","journal":"Nucleic acids research","confidence":"Medium","confidence_rationale":"Tier 2 / Weak — direct ssRNA binding by EMSA and localization by imaging confirmed, but ALBA4 is one of three co-studied paralogs and individual contributions are not fully resolved; single lab.","pmids":["22167473"],"is_preprint":false,"attribution":[{"species":"Plasmodium falciparum","strain":""}]},{"year":2017,"finding":"In P. yoelii, ALBA4 is required for normal development of transmission stages (sexual and sporozoite); genetic disruption of ALBA4 impairs transmission stage development. ALBA4 associates with stage-specific and stage-independent protein partners (identified by proteomics across asexual blood, sexual, and sporozoite stages) and regulates distinct mRNA targets in each stage, producing opposing mRNA fates.","method":"Genetic knockout/disruption, quantitative proteomics (protein complex comparison across stages), transcriptomics (mRNA targets)","journal":"Molecular microbiology","confidence":"High","confidence_rationale":"Tier 2 / Moderate — genetic loss-of-function with defined phenotypic readout, proteomics of the complex across multiple stages, and transcriptomics of mRNA targets; multiple orthogonal methods in a single rigorous study.","pmids":["28787542"],"is_preprint":false,"attribution":[{"species":"Plasmodium yoelii","strain":""}]},{"year":2025,"finding":"Ectopic overexpression of ALBA4 (PfAlba4) from an episome under a strong constitutive promoter was well-tolerated by P. falciparum and did not significantly perturb the steady-state transcriptome during intra-erythrocytic development, in contrast to overexpression of PfAlba2/3 which was detrimental. ALBA4 overexpression appeared to enhance var mRNA levels, linking it to subtelomeric/virulence gene regulation.","method":"Episomal overexpression, RNA-seq (differential gene expression analysis)","journal":"Microbiology spectrum","confidence":"Medium","confidence_rationale":"Tier 2 / Weak — overexpression with RNA-seq readout establishes a functional phenotype and transcriptomic consequence; single lab, single study, gain-of-function rather than loss-of-function.","pmids":["39868986"],"is_preprint":false,"attribution":[{"species":"Plasmodium falciparum","strain":""}]}],"current_model":"ALBA4 (PF3D7_1347500) is an Alba-domain DNA/RNA-binding protein that localizes to the nuclear periphery in early blood stages and redistributes to cytoplasmic puncta at the trophozoite-schizont transition; in P. yoelii it is required for transmission stage development, forms stage-specific protein complexes with both conserved and stage-restricted partners, and regulates distinct mRNA fates across life cycle stages, while in P. falciparum its overexpression is well-tolerated and modestly elevates var gene mRNA levels without broadly perturbing the transcriptome."},"narrative":{"mechanistic_narrative":"ALBA4 (PF3D7_1347500) is an Alba-domain nucleic-acid-binding protein that couples subtelomeric chromatin and stage-specific mRNA regulation in Plasmodium, one of four PfAlba paralogs [PMID:22167473]. In P. falciparum it was isolated within a molecular complex associated with the parasite-specific TARE6 subtelomeric region and binds TARE6 repeat DNA directly by EMSA [PMID:22167473], and it also binds single-stranded RNA, with its localization shifting from the nuclear periphery in early blood stages to cytoplasmic puncta at the trophozoite-schizont transition — indicating a developmentally regulated switch between nuclear and cytoplasmic roles [PMID:22167473]. Consistent with an RNA-regulatory function, ectopic overexpression of ALBA4 in P. falciparum is well-tolerated and does not broadly perturb the intra-erythrocytic transcriptome, yet elevates var mRNA levels, tying it to subtelomeric/virulence gene regulation [PMID:39868986]. In P. yoelii, genetic disruption of ALBA4 impairs development of transmission stages, where the protein assembles into stage-specific and stage-independent complexes and directs distinct, opposing mRNA fates across asexual blood, sexual, and sporozoite stages [PMID:28787542]. The identities of ALBA4's individual DNA/RNA targets versus those bound by its co-isolated paralogs, and the structural basis of its complex assembly, have not been resolved in the available corpus.","teleology":[{"year":2011,"claim":"Establishing whether ALBA4 has intrinsic nucleic-acid-binding activity and a chromatin association defined its first molecular role: it binds TARE6 subtelomeric repeat DNA within an isolated complex.","evidence":"Complex co-purification and EMSA with TARE6 probes in P. falciparum","pmids":["22167473"],"confidence":"Medium","gaps":["ALBA4's binding was not individually distinguished from the co-isolated paralogs","the in vivo consequence of TARE6 binding was not tested","no structural basis for DNA recognition"],"attribution":[{"species":"Plasmodium falciparum","strain":""}]},{"year":2011,"claim":"Demonstrating ssRNA binding and a stage-dependent nuclear-to-cytoplasmic relocalization reframed ALBA4 as a candidate RNA regulator whose function is developmentally switched rather than purely a chromatin factor.","evidence":"EMSA with ssRNA probes and immunolocalization across blood-stage development in P. falciparum","pmids":["22167473"],"confidence":"Medium","gaps":["individual paralog contributions to RNA binding not fully resolved","the specific mRNAs bound in blood stages were not identified","the trigger for relocalization is unknown"],"attribution":[{"species":"Plasmodium falciparum","strain":""}]},{"year":2017,"claim":"Loss-of-function genetics in a rodent malaria model established ALBA4 as functionally required in vivo and connected its RNA binding to stage-specific control of transcript fate.","evidence":"Genetic knockout with transmission-stage phenotyping, stage-resolved proteomics of the complex, and transcriptomic mapping of mRNA targets in P. yoelii","pmids":["28787542"],"confidence":"High","gaps":["the mechanism producing opposing mRNA fates is not defined","whether the P. falciparum ortholog is similarly required for transmission was not tested","partner identities driving stage-specificity not individually validated"],"attribution":[{"species":"Plasmodium yoelii","strain":""}]},{"year":2025,"claim":"Gain-of-function in P. falciparum distinguished ALBA4 from its paralogs functionally and linked it specifically to virulence-gene expression.","evidence":"Episomal constitutive overexpression with RNA-seq differential expression in P. falciparum","pmids":["39868986"],"confidence":"Medium","gaps":["gain-of-function does not establish requirement for var regulation","the mechanism by which var mRNA is elevated is unknown","single lab, single study"],"attribution":[{"species":"Plasmodium falciparum","strain":""}]},{"year":null,"claim":"The direct in vivo DNA and RNA targets of ALBA4 itself (as opposed to its complex), the structural basis of its stage-specific complex assembly, and whether its P. falciparum function in transmission mirrors the P. yoelii requirement remain unresolved.","evidence":"","pmids":[],"confidence":"Medium","gaps":["no genome-wide ALBA4-specific binding map","no structural model of ALBA4 or its complexes","P. falciparum transmission-stage requirement untested"],"attribution":[]}],"mechanism_profile":{"molecular_activity":[],"localization":[],"pathway":[],"complexes":["PfAlba complex associated with the TARE6 subtelomeric region","Stage-specific and stage-independent ALBA4 protein complexes (P. yoelii)"],"partners":["PFALBA PARALOGS (CO-ISOLATED IN THE TARE6-ASSOCIATED COMPLEX)"],"other_free_text":["Binds P. falciparum-specific TARE6 subtelomeric repeat DNA [#0]","Overexpression in P. falciparum elevates var (virulence) gene mRNA without broadly perturbing the transcriptome [#3]","In P. yoelii, disruption impairs transmission-stage (sexual and sporozoite) development and the protein directs opposing mRNA fates across life-cycle stages [#2]","Localization is developmentally regulated, shifting from nuclear periphery to cytoplasmic puncta at the trophozoite-schizont transition [#1]"]}},"prefetch_data":{},"corpus_meta":[{"pmid":"10693754","id":"PMC_10693754","title":"A simple RNA analysis method shows var and rif multigene family expression patterns in Plasmodium falciparum.","date":"2000","source":"Molecular and biochemical parasitology","url":"https://pubmed.ncbi.nlm.nih.gov/10693754","citation_count":234,"is_preprint":false,"source_species":["Pf"],"role":"primary","match_terms":["RNA"],"competing_organism_flag":false,"competing_organism_match":"","competing_organism_only":false},{"pmid":"26525978","id":"PMC_26525978","title":"A bioinformatic survey of RNA-binding proteins in Plasmodium.","date":"2015","source":"BMC genomics","url":"https://pubmed.ncbi.nlm.nih.gov/26525978","citation_count":62,"is_preprint":false,"source_species":["Pf"],"role":"primary","match_terms":["RNA"],"competing_organism_flag":false,"competing_organism_match":"","competing_organism_only":false},{"pmid":"22006844","id":"PMC_22006844","title":"Identification and molecular characterization of an Alba-family protein from human malaria parasite Plasmodium falciparum.","date":"2011","source":"Nucleic acids research","url":"https://pubmed.ncbi.nlm.nih.gov/22006844","citation_count":60,"is_preprint":false,"source_species":["Pf"],"role":"primary","match_terms":["DNA"],"competing_organism_flag":false,"competing_organism_match":"","competing_organism_only":false},{"pmid":"22167473","id":"PMC_22167473","title":"PfAlbas constitute a new eukaryotic DNA/RNA-binding protein family in malaria parasites.","date":"2011","source":"Nucleic acids research","url":"https://pubmed.ncbi.nlm.nih.gov/22167473","citation_count":60,"is_preprint":false,"source_species":["Pf"],"role":"primary","match_terms":["curated_ref"],"competing_organism_flag":false,"competing_organism_match":"","competing_organism_only":false},{"pmid":"27230797","id":"PMC_27230797","title":"Translational regulation in blood stages of the malaria parasite Plasmodium spp.: systems-wide studies pave the way.","date":"2016","source":"Wiley interdisciplinary reviews. RNA","url":"https://pubmed.ncbi.nlm.nih.gov/27230797","citation_count":54,"is_preprint":false,"source_species":["Pf"],"role":"primary","match_terms":["RNA"],"competing_organism_flag":false,"competing_organism_match":"","competing_organism_only":false},{"pmid":"7976752","id":"PMC_7976752","title":"The ribosomal RNA genes of Plasmodium.","date":"1994","source":"Advances in parasitology","url":"https://pubmed.ncbi.nlm.nih.gov/7976752","citation_count":46,"is_preprint":false,"source_species":["Pf"],"role":"primary","match_terms":["RNA"],"competing_organism_flag":false,"competing_organism_match":"","competing_organism_only":false},{"pmid":"28787542","id":"PMC_28787542","title":"ALBA4 modulates its stage-specific interactions and specific mRNA fates during Plasmodium yoelii growth and transmission.","date":"2017","source":"Molecular microbiology","url":"https://pubmed.ncbi.nlm.nih.gov/28787542","citation_count":38,"is_preprint":false,"source_species":["Pf"],"role":"primary","match_terms":["ALBA4","RNA"],"competing_organism_flag":false,"competing_organism_match":"","competing_organism_only":false},{"pmid":"39868986","id":"PMC_39868986","title":"Ectopic overexpression of Plasmodium falciparum DNA-/RNA-binding Alba proteins misregulates virulence gene homeostasis during asexual blood development.","date":"2025","source":"Microbiology spectrum","url":"https://pubmed.ncbi.nlm.nih.gov/39868986","citation_count":3,"is_preprint":false,"source_species":["Pf"],"role":"primary","match_terms":["PfALBA4"],"competing_organism_flag":false,"competing_organism_match":"","competing_organism_only":false}],"cost":{"stage1":{"model":"claude-sonnet-4-6","input_tokens":6415,"output_tokens":1231,"usd":0.018855,"stage1_stop_reason":"end_turn"},"stage2":{"model":"claude-opus-4-8","input_tokens":6155,"output_tokens":2451,"usd":0.046025,"stage2_stop_reason":"end_turn"},"total_usd":0.06488,"stage1_batch_id":"msgbatch_011BPjN2BL33F8cJXD1r7V7T","stage2_batch_id":"msgbatch_01Qwg6vP7qxkpL6Gsc7tajsb","note":"batch pricing = 50% of standard"},"stage1_raw":"```json\n{\n  \"discoveries\": [\n    {\n      \"year\": 2011,\n      \"finding\": \"ALBA4 (one of four PfAlba paralogs) was isolated as part of a molecular complex associated with the P. falciparum-specific TARE6 subtelomeric region, and shown by electromobility shift assays (EMSAs) to bind TARE6 repeat DNA sequences.\",\n      \"method\": \"Co-purification/complex isolation, EMSA\",\n      \"journal\": \"Nucleic acids research\",\n      \"confidence\": \"Medium\",\n      \"confidence_rationale\": \"Tier 2 / Weak — EMSA directly demonstrates DNA binding, but ALBA4 is one of three paralogs co-isolated and the abstract does not individually distinguish ALBA4's binding from the others; single lab, single study.\",\n      \"pmids\": [\"22167473\"],\n      \"is_preprint\": false,\n      \"attribution\": [{\"species\": \"Plasmodium falciparum\", \"strain\": \"\"}]\n    },\n    {\n      \"year\": 2011,\n      \"finding\": \"ALBA4 (as part of the PfAlba complex) binds single-stranded RNA (ssRNA) as demonstrated by EMSA, with different binding preferences among the paralogs; intracellular localization shifts from nuclear periphery in early blood stages to a cytoplasmic punctate pattern at trophozoite-schizont transition, indicating developmentally regulated subcellular localization.\",\n      \"method\": \"EMSA (ssRNA probes), fluorescence microscopy/immunolocalization\",\n      \"journal\": \"Nucleic acids research\",\n      \"confidence\": \"Medium\",\n      \"confidence_rationale\": \"Tier 2 / Weak — direct ssRNA binding by EMSA and localization by imaging confirmed, but ALBA4 is one of three co-studied paralogs and individual contributions are not fully resolved; single lab.\",\n      \"pmids\": [\"22167473\"],\n      \"is_preprint\": false,\n      \"attribution\": [{\"species\": \"Plasmodium falciparum\", \"strain\": \"\"}]\n    },\n    {\n      \"year\": 2017,\n      \"finding\": \"In P. yoelii, ALBA4 is required for normal development of transmission stages (sexual and sporozoite); genetic disruption of ALBA4 impairs transmission stage development. ALBA4 associates with stage-specific and stage-independent protein partners (identified by proteomics across asexual blood, sexual, and sporozoite stages) and regulates distinct mRNA targets in each stage, producing opposing mRNA fates.\",\n      \"method\": \"Genetic knockout/disruption, quantitative proteomics (protein complex comparison across stages), transcriptomics (mRNA targets)\",\n      \"journal\": \"Molecular microbiology\",\n      \"confidence\": \"High\",\n      \"confidence_rationale\": \"Tier 2 / Moderate — genetic loss-of-function with defined phenotypic readout, proteomics of the complex across multiple stages, and transcriptomics of mRNA targets; multiple orthogonal methods in a single rigorous study.\",\n      \"pmids\": [\"28787542\"],\n      \"is_preprint\": false,\n      \"attribution\": [{\"species\": \"Plasmodium yoelii\", \"strain\": \"\"}]\n    },\n    {\n      \"year\": 2025,\n      \"finding\": \"Ectopic overexpression of ALBA4 (PfAlba4) from an episome under a strong constitutive promoter was well-tolerated by P. falciparum and did not significantly perturb the steady-state transcriptome during intra-erythrocytic development, in contrast to overexpression of PfAlba2/3 which was detrimental. ALBA4 overexpression appeared to enhance var mRNA levels, linking it to subtelomeric/virulence gene regulation.\",\n      \"method\": \"Episomal overexpression, RNA-seq (differential gene expression analysis)\",\n      \"journal\": \"Microbiology spectrum\",\n      \"confidence\": \"Medium\",\n      \"confidence_rationale\": \"Tier 2 / Weak — overexpression with RNA-seq readout establishes a functional phenotype and transcriptomic consequence; single lab, single study, gain-of-function rather than loss-of-function.\",\n      \"pmids\": [\"39868986\"],\n      \"is_preprint\": false,\n      \"attribution\": [{\"species\": \"Plasmodium falciparum\", \"strain\": \"\"}]\n    }\n  ],\n  \"current_model\": \"ALBA4 (PF3D7_1347500) is an Alba-domain DNA/RNA-binding protein that localizes to the nuclear periphery in early blood stages and redistributes to cytoplasmic puncta at the trophozoite-schizont transition; in P. yoelii it is required for transmission stage development, forms stage-specific protein complexes with both conserved and stage-restricted partners, and regulates distinct mRNA fates across life cycle stages, while in P. falciparum its overexpression is well-tolerated and modestly elevates var gene mRNA levels without broadly perturbing the transcriptome.\"\n}\n```","stage2_raw":"{\n  \"mechanistic_narrative\": \"ALBA4 (PF3D7_1347500) is an Alba-domain nucleic-acid-binding protein that couples subtelomeric chromatin and stage-specific mRNA regulation in Plasmodium, one of four PfAlba paralogs [#0]. In P. falciparum it was isolated within a molecular complex associated with the parasite-specific TARE6 subtelomeric region and binds TARE6 repeat DNA directly by EMSA [#0], and it also binds single-stranded RNA, with its localization shifting from the nuclear periphery in early blood stages to cytoplasmic puncta at the trophozoite-schizont transition — indicating a developmentally regulated switch between nuclear and cytoplasmic roles [#1]. Consistent with an RNA-regulatory function, ectopic overexpression of ALBA4 in P. falciparum is well-tolerated and does not broadly perturb the intra-erythrocytic transcriptome, yet elevates var mRNA levels, tying it to subtelomeric/virulence gene regulation [#3]. In P. yoelii, genetic disruption of ALBA4 impairs development of transmission stages, where the protein assembles into stage-specific and stage-independent complexes and directs distinct, opposing mRNA fates across asexual blood, sexual, and sporozoite stages [#2]. The identities of ALBA4's individual DNA/RNA targets versus those bound by its co-isolated paralogs, and the structural basis of its complex assembly, have not been resolved in the available corpus.\",\n  \"teleology\": [\n    {\n      \"year\": 2011,\n      \"claim\": \"Establishing whether ALBA4 has intrinsic nucleic-acid-binding activity and a chromatin association defined its first molecular role: it binds TARE6 subtelomeric repeat DNA within an isolated complex.\",\n      \"evidence\": \"Complex co-purification and EMSA with TARE6 probes in P. falciparum\",\n      \"pmids\": [\"22167473\"],\n      \"confidence\": \"Medium\",\n      \"gaps\": [\"ALBA4's binding was not individually distinguished from the co-isolated paralogs\", \"the in vivo consequence of TARE6 binding was not tested\", \"no structural basis for DNA recognition\"],\n      \"attribution\": [{\"species\": \"Plasmodium falciparum\", \"strain\": \"\"}]\n    },\n    {\n      \"year\": 2011,\n      \"claim\": \"Demonstrating ssRNA binding and a stage-dependent nuclear-to-cytoplasmic relocalization reframed ALBA4 as a candidate RNA regulator whose function is developmentally switched rather than purely a chromatin factor.\",\n      \"evidence\": \"EMSA with ssRNA probes and immunolocalization across blood-stage development in P. falciparum\",\n      \"pmids\": [\"22167473\"],\n      \"confidence\": \"Medium\",\n      \"gaps\": [\"individual paralog contributions to RNA binding not fully resolved\", \"the specific mRNAs bound in blood stages were not identified\", \"the trigger for relocalization is unknown\"],\n      \"attribution\": [{\"species\": \"Plasmodium falciparum\", \"strain\": \"\"}]\n    },\n    {\n      \"year\": 2017,\n      \"claim\": \"Loss-of-function genetics in a rodent malaria model established ALBA4 as functionally required in vivo and connected its RNA binding to stage-specific control of transcript fate.\",\n      \"evidence\": \"Genetic knockout with transmission-stage phenotyping, stage-resolved proteomics of the complex, and transcriptomic mapping of mRNA targets in P. yoelii\",\n      \"pmids\": [\"28787542\"],\n      \"confidence\": \"High\",\n      \"gaps\": [\"the mechanism producing opposing mRNA fates is not defined\", \"whether the P. falciparum ortholog is similarly required for transmission was not tested\", \"partner identities driving stage-specificity not individually validated\"],\n      \"attribution\": [{\"species\": \"Plasmodium yoelii\", \"strain\": \"\"}]\n    },\n    {\n      \"year\": 2025,\n      \"claim\": \"Gain-of-function in P. falciparum distinguished ALBA4 from its paralogs functionally and linked it specifically to virulence-gene expression.\",\n      \"evidence\": \"Episomal constitutive overexpression with RNA-seq differential expression in P. falciparum\",\n      \"pmids\": [\"39868986\"],\n      \"confidence\": \"Medium\",\n      \"gaps\": [\"gain-of-function does not establish requirement for var regulation\", \"the mechanism by which var mRNA is elevated is unknown\", \"single lab, single study\"],\n      \"attribution\": [{\"species\": \"Plasmodium falciparum\", \"strain\": \"\"}]\n    },\n    {\n      \"year\": null,\n      \"claim\": \"The direct in vivo DNA and RNA targets of ALBA4 itself (as opposed to its complex), the structural basis of its stage-specific complex assembly, and whether its P. falciparum function in transmission mirrors the P. yoelii requirement remain unresolved.\",\n      \"evidence\": \"\",\n      \"pmids\": [],\n      \"confidence\": \"Medium\",\n      \"gaps\": [\"no genome-wide ALBA4-specific binding map\", \"no structural model of ALBA4 or its complexes\", \"P. falciparum transmission-stage requirement untested\"],\n      \"attribution\": []\n    }\n  ],\n  \"mechanism_profile\": {\n    \"molecular_activity\": [\n      {\"term_id\": \"GO:0003690\", \"supporting_discovery_ids\": [0]},\n      {\"term_id\": \"GO:0003727\", \"supporting_discovery_ids\": [1]},\n      {\"term_id\": \"GO:0003729\", \"supporting_discovery_ids\": [2]}\n    ],\n    \"localization\": [\n      {\"term_id\": \"GO:0034399\", \"supporting_discovery_ids\": [1]},\n      {\"term_id\": \"GO:0005737\", \"supporting_discovery_ids\": [1]}\n    ],\n    \"pathway\": [\n      {\"term_id\": \"GO:0006355\", \"supporting_discovery_ids\": [3]},\n      {\"term_id\": \"GO:0006402\", \"supporting_discovery_ids\": [2]},\n      {\"term_id\": \"GO:0019953\", \"supporting_discovery_ids\": [2]}\n    ],\n    \"complexes\": [\n      \"PfAlba complex associated with the TARE6 subtelomeric region\",\n      \"Stage-specific and stage-independent ALBA4 protein complexes (P. yoelii)\"\n    ],\n    \"partners\": [\n      \"PfAlba paralogs (co-isolated in the TARE6-associated complex)\"\n    ],\n    \"other_free_text\": [\n      \"Binds P. falciparum-specific TARE6 subtelomeric repeat DNA [#0]\",\n      \"Overexpression in P. falciparum elevates var (virulence) gene mRNA without broadly perturbing the transcriptome [#3]\",\n      \"In P. yoelii, disruption impairs transmission-stage (sexual and sporozoite) development and the protein directs opposing mRNA fates across life-cycle stages [#2]\",\n      \"Localization is developmentally regulated, shifting from nuclear periphery to cytoplasmic puncta at the trophozoite-schizont transition [#1]\"\n    ]\n  }\n}","audit_flag":null,"strains":[{"strain":"Pf3D7","gene_id":"PF3D7_1347500","name":null,"product":"DNA/RNA-binding protein Alba 4","uniprot_acc":null,"chromosome":null,"start_pos":null},{"strain":"PbANKA","gene_id":"PBANKA_1360300","name":null,"product":"DNA/RNA-binding protein Alba 4, putative","uniprot_acc":null,"chromosome":null,"start_pos":null},{"strain":"PkH","gene_id":"PKNH_1253400","name":null,"product":"DNA/RNA-binding protein Alba 4, putative","uniprot_acc":null,"chromosome":null,"start_pos":null}],"gene_symbol":"ALBA4","evaluation":null}