{"gene":"PF3D7_0527000","run_date":"2026-09-07T10:55:52","timeline":{"discoveries":[],"current_model":"No mechanistic findings in the available literature."},"narrative":{"mechanistic_narrative":"No mechanistic discoveries found in literature.","teleology":[],"mechanism_profile":null},"prefetch_data":{},"corpus_meta":[{"pmid":"6204268","id":"PMC_6204268","title":"Determination of nuclear DNA of five eucoccidian parasites, Isospora (Toxoplasma) gondii, Sarcocystis cruzi, Eimeria tenella, E. acervulina and Plasmodium berghei, with special reference to gamontogenesis and meiosis in I. (T.) gondii.","date":"1984","source":"Parasitology","url":"https://pubmed.ncbi.nlm.nih.gov/6204268","citation_count":88,"is_preprint":false,"source_species":["Pf"],"role":"primary","match_terms":["DNA"],"competing_organism_flag":true,"competing_organism_match":"Toxoplasma","competing_organism_only":false},{"pmid":"3088783","id":"PMC_3088783","title":"Rapid repeated DNA replication during microgametogenesis and DNA synthesis in young zygotes of Plasmodium berghei.","date":"1986","source":"Transactions of the Royal Society of Tropical Medicine and Hygiene","url":"https://pubmed.ncbi.nlm.nih.gov/3088783","citation_count":61,"is_preprint":false,"source_species":["Pf"],"role":"primary","match_terms":["DNA"],"competing_organism_flag":false,"competing_organism_match":"","competing_organism_only":false},{"pmid":"15948708","id":"PMC_15948708","title":"DNA-[adenine] methylation in lower eukaryotes.","date":"2005","source":"Biochemistry. Biokhimiia","url":"https://pubmed.ncbi.nlm.nih.gov/15948708","citation_count":42,"is_preprint":false,"source_species":["Pf"],"role":"primary","match_terms":["DNA"],"competing_organism_flag":false,"competing_organism_match":"","competing_organism_only":false},{"pmid":"2892060","id":"PMC_2892060","title":"From Laveran's discovery to DNA probes: new trends in diagnosis of malaria.","date":"1987","source":"Lancet (London, England)","url":"https://pubmed.ncbi.nlm.nih.gov/2892060","citation_count":31,"is_preprint":false,"source_species":["Pf"],"role":"primary","match_terms":["DNA"],"competing_organism_flag":false,"competing_organism_match":"","competing_organism_only":false},{"pmid":"41309744","id":"PMC_41309744","title":"The impact of Iso-mukaadial acetate on Plasmodium falciparum transcriptional gene regulation.","date":"2025","source":"Scientific reports","url":"https://pubmed.ncbi.nlm.nih.gov/41309744","citation_count":0,"is_preprint":false,"source_species":["Pf"],"role":"primary","match_terms":["MCM3"],"competing_organism_flag":false,"competing_organism_match":"","competing_organism_only":false}],"cost":{"stage1":{"model":"claude-sonnet-4-6","input_tokens":4754,"output_tokens":34,"usd":0.007386,"stage1_stop_reason":"end_turn"},"stage2":{"model":"","input_tokens":0,"output_tokens":0,"usd":0.0},"total_usd":0.007386,"stage1_batch_id":"msgbatch_01DbiymDmubkPpYvdbAu5a7V","stage2_batch_id":"msgbatch_012TbrWvMRH129T7PQ4SmvrJ","note":"batch pricing = 50% of standard"},"stage1_raw":"```json\n{\n  \"discoveries\": [],\n  \"current_model\": \"No mechanistic findings in the available literature.\"\n}\n```","stage2_raw":"","audit_flag":{"gene":"PF3D7_0527000","tier":"COVERAGE","verdict":"Coverage note","subtype":"corpus_generic","uniprot_band":"empty","rules_fired":"R1","issue":"R1: gene named in 1/97 (1%) of its corpus abstracts and Stage 1 extracted no discoveries — no gene-specific literature retrieved"},"strains":[{"strain":"Pf3D7","gene_id":"PF3D7_0527000","name":null,"product":"DNA replication licensing factor MCM3, putative","uniprot_acc":null,"chromosome":null,"start_pos":null},{"strain":"PbANKA","gene_id":"PBANKA_1241800","name":null,"product":"DNA replication licensing factor MCM3, putative","uniprot_acc":null,"chromosome":null,"start_pos":null},{"strain":"PkH","gene_id":"PKNH_1005700","name":null,"product":"DNA replication licensing factor MCM3, putative","uniprot_acc":null,"chromosome":null,"start_pos":null}],"gene_symbol":"MCM3","evaluation":null}