{"gene":"PBANKA_1349200","run_date":"2026-09-07T10:55:51","timeline":{"discoveries":[{"year":2002,"finding":"MSRP1 (designated MSRP-1 in P. falciparum) was identified as a protein that interacts with the amino-terminal region of MSP-1 in P. yoelii using the yeast two-hybrid system, and in vitro binding experiments confirmed the interaction between MSRP-1 and the amino-terminal region of P. falciparum MSP-1. Immunofluorescence studies colocalized MSRP expression with the amino-terminal portion of MSP-1 on the surfaces of trophozoites.","method":"Yeast two-hybrid screen, in vitro binding assay, immunofluorescence microscopy","journal":"Eukaryotic cell","confidence":"Medium","confidence_rationale":"Tier 3 / Moderate — yeast two-hybrid plus in vitro binding plus immunofluorescence, single lab, but three orthogonal methods","pmids":["12477792"],"is_preprint":false,"attribution":[{"species":"Plasmodium falciparum","strain":""},{"species":"Plasmodium yoelii","strain":""}]},{"year":2015,"finding":"In Plasmodium berghei, the ortholog of MSRP1 (referred to as PbMSRP1) was identified as a direct binding partner of host P-selectin. The interaction was mediated via the N-terminus of the MSP7-family protein and the C-type lectin and EGF-like domains of P-selectin. When complexed with PbMSRP1, P-selectin could no longer bind its endogenous carbohydrate ligand Sialyl-Lewis(X), suggesting a mechanism for immunomodulation.","method":"Systematic extracellular protein interaction screen, biochemical binding assays","journal":"Malaria journal","confidence":"Medium","confidence_rationale":"Tier 3 / Moderate — direct binding assay identifying interaction and functional consequence (blocking of P-selectin ligand binding), single lab, two orthogonal methods","pmids":["26045295"],"is_preprint":false,"attribution":[{"species":"Plasmodium berghei","strain":""},{"species":"Plasmodium falciparum","strain":""}]},{"year":2015,"finding":"In P. berghei, a triple knockout of msp7/mspr1/mspr2 (the gene family including PBANKA_1349200/MSRP1) showed no impairment of life cycle progression, indicating that MSRP1 is dispensable for asexual blood-stage development in P. berghei.","method":"Genetic triple knockout, life cycle progression assay","journal":"Molecular and biochemical parasitology","confidence":"Medium","confidence_rationale":"Tier 2 / Weak — clean genetic knockout with defined phenotypic readout (no phenotype), single lab, single method; negative result explicitly reported","pmids":["26222913"],"is_preprint":false,"attribution":[{"species":"Plasmodium berghei","strain":""}]},{"year":2026,"finding":"In P. falciparum, MSRP1 expression is dependent on the transcription factor AP2-G: parasites expressing a non-DNA-binding AP2-G.L2163 mutant did not express MSRP1, whereas functional AP2-G.V2163 was required for MSRP1 expression. This places MSRP1 as a downstream transcriptional target of AP2-G in the sexual commitment pathway, and its expression distinguishes early from late sexually committed schizonts.","method":"Mutant AP2-G parasite lines (forward and reverse mutation editing), gene expression analysis","journal":"Nature communications","confidence":"Medium","confidence_rationale":"Tier 2 / Moderate — genetic epistasis using forward and reverse mutation editing with defined expression readout for MSRP1, single lab, two orthogonal genetic approaches","pmids":["41547993"],"is_preprint":false,"attribution":[{"species":"Plasmodium falciparum","strain":""}]},{"year":2025,"finding":"In P. falciparum, MSRP1 expression requires functional AP2-G (with valine at position 2163); a V2163L mutation that abolishes AP2-G DNA binding eliminates MSRP1 expression. MSRP1 expression can therefore be used as a marker to distinguish early and late sexually committed schizonts. This is a preprint version of the same finding as PMID:41547993.","method":"Mutant AP2-G parasite lines (forward and reverse mutation editing), gene expression analysis","journal":"bioRxiv","confidence":"Low","confidence_rationale":"Tier 2 / Weak — preprint, same finding as published peer-reviewed version (PMID:41547993); downgraded to Low as it is a preprint duplicate","pmids":["40568120"],"is_preprint":true,"attribution":[{"species":"Plasmodium falciparum","strain":""}]},{"year":2013,"finding":"Members of the MSP-7 related protein (MSRP) family in P. falciparum, including MSRP members, were identified as PEXEL/HT-negative exported proteins (PNEPs), indicating unanticipated export into the host erythrocyte without a classical export motif. This was unexpected given the known surface localization of MSP7-family proteins.","method":"Reporter export assay, protein localization studies","journal":"PLoS pathogens","confidence":"Low","confidence_rationale":"Tier 3 / Weak — identification of family members as PNEPs by reporter assay; the abstract does not specify which MSRP family member was confirmed for export, making the direct attribution to MSRP1/PBANKA_1349200 uncertain","pmids":["23950716"],"is_preprint":false,"attribution":[{"species":"Plasmodium falciparum","strain":""}]}],"current_model":"PBANKA_1349200 (MSRP1) is an MSP7-like merozoite surface protein in Plasmodium berghei that interacts with the amino-terminal region of MSP-1 and directly binds host P-selectin via its N-terminus (blocking P-selectin's interaction with its endogenous ligand Sialyl-Lewis X), while in P. falciparum its expression is transcriptionally controlled downstream of the sexual commitment factor AP2-G, marking early sexually committed schizonts; genetic deletion of the P. berghei family locus (including MSRP1) causes no detectable blood-stage growth phenotype."},"narrative":{"mechanistic_narrative":"PBANKA_1349200 (MSRP1) is an MSP7-like merozoite surface protein whose characterized biology centers on protein-protein interactions at the host-parasite interface and on transcriptional regulation during sexual commitment [PMID:12477792, PMID:26045295, PMID:41547993]. MSRP1 was first identified as an interaction partner of the amino-terminal region of MSP-1, with its expression colocalizing with the MSP-1 N-terminus on the parasite surface [PMID:12477792]. In P. berghei, MSRP1 directly binds host P-selectin through its N-terminus, engaging the C-type lectin and EGF-like domains of P-selectin; the resulting complex prevents P-selectin from binding its endogenous carbohydrate ligand Sialyl-Lewis(X), implicating MSRP1 in immunomodulation [PMID:26045295]. In P. falciparum, MSRP1 expression is a downstream transcriptional target of the sexual commitment factor AP2-G: a DNA-binding-deficient AP2-G mutant abolishes MSRP1 expression, and MSRP1 expression marks early sexually committed schizonts [PMID:41547993]. Genetic deletion of the P. berghei MSP7 family locus encompassing MSRP1 produces no detectable blood-stage or life-cycle phenotype, indicating MSRP1 is dispensable for asexual development in that species [PMID:26222913]. Beyond these interaction, regulatory, and dispensability findings, no enzymatic activity or higher-resolution structural mechanism for MSRP1 has been characterized in the available corpus.","teleology":[{"year":2002,"claim":"Establishing whether MSRP1 physically associates with the merozoite surface complex, this work placed MSRP1 as a binding partner of MSP-1 rather than an independent surface protein.","evidence":"Yeast two-hybrid screen, in vitro binding, and immunofluorescence colocalization with the MSP-1 N-terminus in P. yoelii and P. falciparum","pmids":["12477792"],"confidence":"Medium","gaps":["Binding region on MSRP1 not mapped","Functional consequence of the MSP-1 interaction not tested","No structural model of the complex"],"attribution":[{"species":"Plasmodium falciparum","strain":""},{"species":"Plasmodium yoelii","strain":""}]},{"year":2015,"claim":"Testing whether MSRP1 engages host receptors, this work identified a direct MSRP1-P-selectin interaction that blocks the receptor's natural ligand, proposing an immunomodulatory role at the host interface.","evidence":"Systematic extracellular protein interaction screen and biochemical binding assays in P. berghei, mapping the N-terminus of MSRP1 to the C-type lectin and EGF-like domains of P-selectin","pmids":["26045295"],"confidence":"Medium","gaps":["Immunomodulatory consequence not demonstrated in vivo","Binding stoichiometry and affinity not quantified","Relationship between P-selectin binding and MSP-1 association unresolved"],"attribution":[{"species":"Plasmodium berghei","strain":""},{"species":"Plasmodium falciparum","strain":""}]},{"year":2015,"claim":"Assessing whether MSRP1 is required for parasite development, gene family deletion showed it is dispensable for asexual blood-stage growth and life-cycle progression in P. berghei.","evidence":"Triple knockout of msp7/msrp1/msrp2 with life cycle progression assay in P. berghei","pmids":["26222913"],"confidence":"Medium","gaps":["Family redundancy prevents isolating MSRP1-specific role","Sexual-stage and transmission phenotypes not examined","Single-gene deletion phenotype not reported"],"attribution":[{"species":"Plasmodium berghei","strain":""}]},{"year":2026,"claim":"Determining how MSRP1 expression is controlled, epistasis analysis placed MSRP1 as a transcriptional target of AP2-G, tying it to the sexual commitment pathway and making it a stage marker.","evidence":"Forward and reverse AP2-G mutation editing (DNA-binding-deficient V2163L versus functional variant) with MSRP1 expression readout in P. falciparum","pmids":["41547993"],"confidence":"Medium","gaps":["Direct AP2-G promoter binding to MSRP1 not shown","Function of MSRP1 in sexual commitment not established","Whether the P. berghei ortholog is similarly regulated unknown"],"attribution":[{"species":"Plasmodium falciparum","strain":""}]},{"year":null,"claim":"Whether MSRP1's surface MSP-1 association, host P-selectin engagement, and AP2-G-driven sexual-stage expression represent one integrated function or distinct stage-specific roles remains unresolved.","evidence":"","pmids":[],"confidence":"Low","gaps":["No molecular activity or enzymatic function defined","No structural characterization of MSRP1","Species divergence in role (P. berghei vs P. falciparum) not reconciled"],"attribution":[]}],"mechanism_profile":{"molecular_activity":[],"localization":[],"pathway":[],"complexes":[],"partners":["MSP-1 (AMINO-TERMINAL REGION)","HOST P-SELECTIN (SELP)","AP2-G (TRANSCRIPTIONAL REGULATOR UPSTREAM OF MSRP1 EXPRESSION)"],"other_free_text":["MSRP1 binds host P-selectin via its N-terminus, blocking P-selectin engagement of Sialyl-Lewis(X), an implicated immunomodulatory mechanism [#1]","Deletion of the P. berghei MSP7 family locus including MSRP1 causes no detectable life-cycle phenotype, indicating dispensability in asexual blood stages [#2]","MSRP1 expression marks early sexually committed schizonts in P. falciparum and depends on functional AP2-G [#3]","MSRP family members were reported as PEXEL/HT-negative exported proteins, but the specific member confirmed for export was not defined, leaving direct attribution to MSRP1 uncertain [#5]"]}},"prefetch_data":{},"corpus_meta":[{"pmid":"25080477","id":"PMC_25080477","title":"New antigens for a multicomponent blood-stage malaria vaccine.","date":"2014","source":"Science translational medicine","url":"https://pubmed.ncbi.nlm.nih.gov/25080477","citation_count":142,"is_preprint":false,"source_species":["Pb"],"role":"primary","match_terms":["MSRP1"],"competing_organism_flag":false,"competing_organism_match":"","competing_organism_only":false},{"pmid":"23950716","id":"PMC_23950716","title":"Identification of new PNEPs indicates a substantial non-PEXEL exportome and underpins common features in Plasmodium falciparum protein export.","date":"2013","source":"PLoS 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confirmed the interaction between MSRP-1 and the amino-terminal region of P. falciparum MSP-1. Immunofluorescence studies colocalized MSRP expression with the amino-terminal portion of MSP-1 on the surfaces of trophozoites.\",\n      \"method\": \"Yeast two-hybrid screen, in vitro binding assay, immunofluorescence microscopy\",\n      \"journal\": \"Eukaryotic cell\",\n      \"confidence\": \"Medium\",\n      \"confidence_rationale\": \"Tier 3 / Moderate — yeast two-hybrid plus in vitro binding plus immunofluorescence, single lab, but three orthogonal methods\",\n      \"pmids\": [\"12477792\"],\n      \"is_preprint\": false,\n      \"attribution\": [\n        {\"species\": \"Plasmodium falciparum\", \"strain\": \"\"},\n        {\"species\": \"Plasmodium yoelii\", \"strain\": \"\"}\n      ]\n    },\n    {\n      \"year\": 2015,\n      \"finding\": \"In Plasmodium berghei, the ortholog of MSRP1 (referred to as PbMSRP1) was identified as a direct binding partner of host P-selectin. The interaction was mediated via the N-terminus of the MSP7-family protein and the C-type lectin and EGF-like domains of P-selectin. When complexed with PbMSRP1, P-selectin could no longer bind its endogenous carbohydrate ligand Sialyl-Lewis(X), suggesting a mechanism for immunomodulation.\",\n      \"method\": \"Systematic extracellular protein interaction screen, biochemical binding assays\",\n      \"journal\": \"Malaria journal\",\n      \"confidence\": \"Medium\",\n      \"confidence_rationale\": \"Tier 3 / Moderate — direct binding assay identifying interaction and functional consequence (blocking of P-selectin ligand binding), single lab, two orthogonal methods\",\n      \"pmids\": [\"26045295\"],\n      \"is_preprint\": false,\n      \"attribution\": [\n        {\"species\": \"Plasmodium berghei\", \"strain\": \"\"},\n        {\"species\": \"Plasmodium falciparum\", \"strain\": \"\"}\n      ]\n    },\n    {\n      \"year\": 2015,\n      \"finding\": \"In P. berghei, a triple knockout of msp7/mspr1/mspr2 (the gene family including PBANKA_1349200/MSRP1) showed no impairment of life cycle progression, indicating that MSRP1 is dispensable for asexual blood-stage development in P. berghei.\",\n      \"method\": \"Genetic triple knockout, life cycle progression assay\",\n      \"journal\": \"Molecular and biochemical parasitology\",\n      \"confidence\": \"Medium\",\n      \"confidence_rationale\": \"Tier 2 / Weak — clean genetic knockout with defined phenotypic readout (no phenotype), single lab, single method; negative result explicitly reported\",\n      \"pmids\": [\"26222913\"],\n      \"is_preprint\": false,\n      \"attribution\": [\n        {\"species\": \"Plasmodium berghei\", \"strain\": \"\"}\n      ]\n    },\n    {\n      \"year\": 2026,\n      \"finding\": \"In P. falciparum, MSRP1 expression is dependent on the transcription factor AP2-G: parasites expressing a non-DNA-binding AP2-G.L2163 mutant did not express MSRP1, whereas functional AP2-G.V2163 was required for MSRP1 expression. This places MSRP1 as a downstream transcriptional target of AP2-G in the sexual commitment pathway, and its expression distinguishes early from late sexually committed schizonts.\",\n      \"method\": \"Mutant AP2-G parasite lines (forward and reverse mutation editing), gene expression analysis\",\n      \"journal\": \"Nature communications\",\n      \"confidence\": \"Medium\",\n      \"confidence_rationale\": \"Tier 2 / Moderate — genetic epistasis using forward and reverse mutation editing with defined expression readout for MSRP1, single lab, two orthogonal genetic approaches\",\n      \"pmids\": [\"41547993\"],\n      \"is_preprint\": false,\n      \"attribution\": [\n        {\"species\": \"Plasmodium falciparum\", \"strain\": \"\"}\n      ]\n    },\n    {\n      \"year\": 2025,\n      \"finding\": \"In P. falciparum, MSRP1 expression requires functional AP2-G (with valine at position 2163); a V2163L mutation that abolishes AP2-G DNA binding eliminates MSRP1 expression. MSRP1 expression can therefore be used as a marker to distinguish early and late sexually committed schizonts. This is a preprint version of the same finding as PMID:41547993.\",\n      \"method\": \"Mutant AP2-G parasite lines (forward and reverse mutation editing), gene expression analysis\",\n      \"journal\": \"bioRxiv\",\n      \"confidence\": \"Low\",\n      \"confidence_rationale\": \"Tier 2 / Weak — preprint, same finding as published peer-reviewed version (PMID:41547993); downgraded to Low as it is a preprint duplicate\",\n      \"pmids\": [\"40568120\"],\n      \"is_preprint\": true,\n      \"attribution\": [\n        {\"species\": \"Plasmodium falciparum\", \"strain\": \"\"}\n      ]\n    },\n    {\n      \"year\": 2013,\n      \"finding\": \"Members of the MSP-7 related protein (MSRP) family in P. falciparum, including MSRP members, were identified as PEXEL/HT-negative exported proteins (PNEPs), indicating unanticipated export into the host erythrocyte without a classical export motif. This was unexpected given the known surface localization of MSP7-family proteins.\",\n      \"method\": \"Reporter export assay, protein localization studies\",\n      \"journal\": \"PLoS pathogens\",\n      \"confidence\": \"Low\",\n      \"confidence_rationale\": \"Tier 3 / Weak — identification of family members as PNEPs by reporter assay; the abstract does not specify which MSRP family member was confirmed for export, making the direct attribution to MSRP1/PBANKA_1349200 uncertain\",\n      \"pmids\": [\"23950716\"],\n      \"is_preprint\": false,\n      \"attribution\": [\n        {\"species\": \"Plasmodium falciparum\", \"strain\": \"\"}\n      ]\n    }\n  ],\n  \"current_model\": \"PBANKA_1349200 (MSRP1) is an MSP7-like merozoite surface protein in Plasmodium berghei that interacts with the amino-terminal region of MSP-1 and directly binds host P-selectin via its N-terminus (blocking P-selectin's interaction with its endogenous ligand Sialyl-Lewis X), while in P. falciparum its expression is transcriptionally controlled downstream of the sexual commitment factor AP2-G, marking early sexually committed schizonts; genetic deletion of the P. berghei family locus (including MSRP1) causes no detectable blood-stage growth phenotype.\"\n}\n```","stage2_raw":"{\n  \"mechanistic_narrative\": \"PBANKA_1349200 (MSRP1) is an MSP7-like merozoite surface protein whose characterized biology centers on protein-protein interactions at the host-parasite interface and on transcriptional regulation during sexual commitment [#0, #1, #3]. MSRP1 was first identified as an interaction partner of the amino-terminal region of MSP-1, with its expression colocalizing with the MSP-1 N-terminus on the parasite surface [#0]. In P. berghei, MSRP1 directly binds host P-selectin through its N-terminus, engaging the C-type lectin and EGF-like domains of P-selectin; the resulting complex prevents P-selectin from binding its endogenous carbohydrate ligand Sialyl-Lewis(X), implicating MSRP1 in immunomodulation [#1]. In P. falciparum, MSRP1 expression is a downstream transcriptional target of the sexual commitment factor AP2-G: a DNA-binding-deficient AP2-G mutant abolishes MSRP1 expression, and MSRP1 expression marks early sexually committed schizonts [#3]. Genetic deletion of the P. berghei MSP7 family locus encompassing MSRP1 produces no detectable blood-stage or life-cycle phenotype, indicating MSRP1 is dispensable for asexual development in that species [#2]. Beyond these interaction, regulatory, and dispensability findings, no enzymatic activity or higher-resolution structural mechanism for MSRP1 has been characterized in the available corpus.\",\n  \"teleology\": [\n    {\n      \"year\": 2002,\n      \"claim\": \"Establishing whether MSRP1 physically associates with the merozoite surface complex, this work placed MSRP1 as a binding partner of MSP-1 rather than an independent surface protein.\",\n      \"evidence\": \"Yeast two-hybrid screen, in vitro binding, and immunofluorescence colocalization with the MSP-1 N-terminus in P. yoelii and P. falciparum\",\n      \"pmids\": [\"12477792\"],\n      \"confidence\": \"Medium\",\n      \"gaps\": [\"Binding region on MSRP1 not mapped\", \"Functional consequence of the MSP-1 interaction not tested\", \"No structural model of the complex\"],\n      \"attribution\": [{\"species\": \"Plasmodium falciparum\", \"strain\": \"\"}, {\"species\": \"Plasmodium yoelii\", \"strain\": \"\"}]\n    },\n    {\n      \"year\": 2015,\n      \"claim\": \"Testing whether MSRP1 engages host receptors, this work identified a direct MSRP1-P-selectin interaction that blocks the receptor's natural ligand, proposing an immunomodulatory role at the host interface.\",\n      \"evidence\": \"Systematic extracellular protein interaction screen and biochemical binding assays in P. berghei, mapping the N-terminus of MSRP1 to the C-type lectin and EGF-like domains of P-selectin\",\n      \"pmids\": [\"26045295\"],\n      \"confidence\": \"Medium\",\n      \"gaps\": [\"Immunomodulatory consequence not demonstrated in vivo\", \"Binding stoichiometry and affinity not quantified\", \"Relationship between P-selectin binding and MSP-1 association unresolved\"],\n      \"attribution\": [{\"species\": \"Plasmodium berghei\", \"strain\": \"\"}, {\"species\": \"Plasmodium falciparum\", \"strain\": \"\"}]\n    },\n    {\n      \"year\": 2015,\n      \"claim\": \"Assessing whether MSRP1 is required for parasite development, gene family deletion showed it is dispensable for asexual blood-stage growth and life-cycle progression in P. berghei.\",\n      \"evidence\": \"Triple knockout of msp7/msrp1/msrp2 with life cycle progression assay in P. berghei\",\n      \"pmids\": [\"26222913\"],\n      \"confidence\": \"Medium\",\n      \"gaps\": [\"Family redundancy prevents isolating MSRP1-specific role\", \"Sexual-stage and transmission phenotypes not examined\", \"Single-gene deletion phenotype not reported\"],\n      \"attribution\": [{\"species\": \"Plasmodium berghei\", \"strain\": \"\"}]\n    },\n    {\n      \"year\": 2026,\n      \"claim\": \"Determining how MSRP1 expression is controlled, epistasis analysis placed MSRP1 as a transcriptional target of AP2-G, tying it to the sexual commitment pathway and making it a stage marker.\",\n      \"evidence\": \"Forward and reverse AP2-G mutation editing (DNA-binding-deficient V2163L versus functional variant) with MSRP1 expression readout in P. falciparum\",\n      \"pmids\": [\"41547993\"],\n      \"confidence\": \"Medium\",\n      \"gaps\": [\"Direct AP2-G promoter binding to MSRP1 not shown\", \"Function of MSRP1 in sexual commitment not established\", \"Whether the P. berghei ortholog is similarly regulated unknown\"],\n      \"attribution\": [{\"species\": \"Plasmodium falciparum\", \"strain\": \"\"}]\n    },\n    {\n      \"year\": null,\n      \"claim\": \"Whether MSRP1's surface MSP-1 association, host P-selectin engagement, and AP2-G-driven sexual-stage expression represent one integrated function or distinct stage-specific roles remains unresolved.\",\n      \"evidence\": \"\",\n      \"pmids\": [],\n      \"confidence\": \"Low\",\n      \"gaps\": [\"No molecular activity or enzymatic function defined\", \"No structural characterization of MSRP1\", \"Species divergence in role (P. berghei vs P. falciparum) not reconciled\"],\n      \"attribution\": []\n    }\n  ],\n  \"mechanism_profile\": {\n    \"molecular_activity\": [\n      {\"term_id\": \"GO:0005102\", \"supporting_discovery_ids\": [0, 1]}\n    ],\n    \"localization\": [\n      {\"term_id\": \"GO:0009986\", \"supporting_discovery_ids\": [0]}\n    ],\n    \"pathway\": [\n      {\"term_id\": \"GO:0060179\", \"supporting_discovery_ids\": [3]}\n    ],\n    \"complexes\": [],\n    \"partners\": [\"MSP-1 (amino-terminal region)\", \"host P-selectin (SELP)\", \"AP2-G (transcriptional regulator upstream of MSRP1 expression)\"],\n    \"other_free_text\": [\n      \"MSRP1 binds host P-selectin via its N-terminus, blocking P-selectin engagement of Sialyl-Lewis(X), an implicated immunomodulatory mechanism [#1]\",\n      \"Deletion of the P. berghei MSP7 family locus including MSRP1 causes no detectable life-cycle phenotype, indicating dispensability in asexual blood stages [#2]\",\n      \"MSRP1 expression marks early sexually committed schizonts in P. falciparum and depends on functional AP2-G [#3]\",\n      \"MSRP family members were reported as PEXEL/HT-negative exported proteins, but the specific member confirmed for export was not defined, leaving direct attribution to MSRP1 uncertain [#5]\"\n    ]\n  }\n}","audit_flag":{"gene":"PBANKA_1349200","tier":"IDENTITY_CHECK","verdict":"identity unverified","subtype":"names_other_cards","uniprot_band":"","rules_fired":"R12","issue":"No cited paper names this card; 4 of 6 cited papers name other catalogue genes (PF3D7_0935400, PF3D7_1222600, PF3D7_0930300). The summary may describe one of those genes."},"strains":[{"strain":"PbANKA","gene_id":"PBANKA_1349200","name":null,"product":"MSP7-like protein","uniprot_acc":null,"chromosome":null,"start_pos":null},{"strain":"PkH","gene_id":"PKNH_1265900","name":null,"product":"MSP7-like protein","uniprot_acc":null,"chromosome":null,"start_pos":null}],"gene_symbol":"MSP7E","evaluation":null}